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Comparative metabolomic profiling of cystine-repleted or -starved NSCLC cells revealed that cystine-starved cells accumulate -glutamyl-di- or tripeptides, which were produced by non-canonical activity of GCLC

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There are also examples of oral medications that when being used experimentally via inhalation cause significant toxicity, such as the death of a research participant following inhalation of hexamethonium [104]

Resveratrol treatment reverses this effect [47] and demonstrates the ability to decrease bacterial burden and improve lung pathology in Mabc -infected mice and zebrafish by activating Sirt3 [140]