In comparison, the stable gastric pentadecapeptide BPC 157, an emerging treatment with potential therapeutic applications, appears to be unrestricted by the limitations seen in previous therapies
DiFeliceantonio and Warren K
However, lignans such as schisandrin A, schisandrin, gomisin A, gomisin C and schisanhenol often exhibit poor water solubility and undergo extensive first-pass metabolism, resulting in low systemic bioavailability
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