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In contrast to BAL fluid, intracellular GSH (overall P = 0.035) was lower in SA ( P = 0.010) compared with HC patients

SAMe is considered to be the universal methyl donor for all methylation reactions including donating a methyl group for DNA and RNA, proteins and neurotransmitters

Produced in every cell, this small molecule is the body's most abundant antioxidant and a key player in liver detoxification

One key factor is the dysregulation of inflammatory pathways, which significantly affects the bladders ability to repair and regenerate

Astrogliosis is prevalent in the epilepsies, and interestingly a mouse forebrain neuron-specific knockout of SOD2 resulted in seizures, oxidative stress, and marked GFAP and vimentin gene upregulation, indicative of astrogliosis resulting from increased neuronal mtROS (Mndez-Armenta et al., 2014