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Second, time-varying confounding due to informative censoring could be present in as-treated analyses, while an intention-to-treat analysis is not susceptible to treatment-related informative censoring

but lower doses led to more modest weight loss:Lower doses had a more favourable side effect profile, too:This triple agonism aims to relieve some of the side effects of GLP1s (nausea, muscle loss), and increase weight loss (so the dose can be lowered)Sources: New obesity drugs - nature.com/articles/d4158 Triple agonist Retatrutide phase 2 trial - nejm.org/doi/full/10.10 full article: openread.academy/en/paper/readi Breakdown of the article: The article discusses the development of new obesity drugs that aim to provide greater and healthier weight loss

Anti-inflammatory and antioxidant effects: GHK-Cu downregulates pro-inflammatory cytokines (like IL-6) and upregulates antioxidant enzymes (such as superoxide dismutase)

doi: 10.1007/s12013-020-00905-6 273