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In the STEP 1 trial extension, participants who stopped semaglutide after 68 weeks regained roughly two-thirds of their prior weight loss within a year, and related cardiometabolic improvements moved back toward baseline

Researchers should prepare and handle all materials using aseptic technique with appropriate sterile equipment, including gloves and protective laboratory equipment

Hypoglycemia: Hypoglycemia is the most common adverse reaction associated with insulin-containing therapy, which may be life-threatening