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Tesamorelin is contraindicated in patients with active malignancy, pituitary disorders affecting GHRH pathways, pregnancy, and in those with disrupted hypothalamic-pituitary function due to surgery, radiation, or trauma

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Long term virological suppression has been shown to significantly reduce the risk of progression to cirrhosis, hepatocellular carcinoma (HCC), and liver related mortality [37, 38]

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small increases in HbA1c observed in some patients [9]