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When the drugs were tested against placebos in clinical trials, both helped patients lose a significant amount of weight

Additionally, tirzepatide suppresses glucagon secretion (a hormone that raises blood glucose), slows gastric emptying, and promotes satiety through central appetite regulation

Come prepared to discuss the following with your doctor: How much weight do I want or need to lose

Known side effects of this treatment include menstrual irregularity

In more advanced renal disease, the potential changes in microbiota during the progression of kidney disease [16] may alter the effects of either drug or their combination