This protein has an effect on cellular senescence and apoptosis, and it interacts with other proteins and signaling pathways to regulate gene expression, affecting cellular responses to stress, DNA repair, and cell survival
Energetically, it is not favorable for Arg123 and Arg127 to be too close to each other due to charge-charge repulsion, despite the presence of a negatively charged Glu40 which attracts them
26 , 30513060.e3054 (2019)
it raises dopamine, serotonin, and endorphins, restoring the chemical balance disrupted by alcohol
Taken together, at early phase of GalN hepatitis, enhanced catalase is the major hydrogen peroxide-detoxifying pathway in proline group, and its detoxifying capacity is higher compared with control group