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A structurally unfolded IGF-1 LR3 will not bind IGF-1R with the same affinity as the correctly folded form, even if HPLC still shows the correct amino acid sequence, because HPLC measures primary sequence not folded conformation

Beyond a certain threshold, higher doses don't produce additional benefits and may actually reduce effectiveness through receptor desensitization

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GSH is a crucial antioxidant within the cell, synthesized from glutamine-derived carbons

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