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These include potential immunogenicity, undefined long-term biosafety profiles of novel nanomaterials, suboptimal drug loading/release kinetics, limited penetration into the invasive tumor margin, and overcoming the immunosuppressive/hypoxic/acidic TME

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About this article Cite this article Panchal, N.K., Swarnalatha, P

The use of GLP-1 receptor agonist drugs has become increasingly common and will likely become more common with the recent FDA approval of oral semaglutide

Obesity also promotes persistent inflammation, which causes fibrotic tissue to infiltrate muscles and surrounding connective tissue, impairing tissue structure, decreasing the release of myokines, and reducing strength and function of muscles