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Lubeck, B

"But with diarrhea, we don't fully know why it happens," Corrado says

The researchers did some pretty cool endocrine testing looking at GnRH pulsatility at the start of the study and after six months of taking 2g/day of ALC, a GnRH test to look at LH and FSH response to GnRH, and a TRH test (I have no idea what that is)

The addition of ibrutinib to CB-839 did not have any remarkable effect on cell proliferation and apoptosis, and no evidence of synergism was found for this combination

This side effect may manifest in the arms, legs, and shoulders