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It has been proposed that the pathophysiology of IIM could be attributed to increased cell death, inadequate removal of cell debris, and excessive autoantigens and pro-inflammatory cytokines, which eventually result in over-stimulated immunological and inflammatory responses (152)

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It has issued multiple advisories over 2025 and 2026 about unauthorized injectable peptides taken from clinics, wellness centres and retail stores, and it is coordinating with the Canada Border Services Agency to intercept shipments at the border