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2017 American College of rheumatology guideline for the prevention and treatment of glucocorticoid-induced osteoporosis

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That said, patients with active diabetes or significant metabolic dysfunction should have any investigational peptide protocol reviewed by their endocrinologist or primary care physician alongside their supervising aesthetic medicine provider

However, current data from SEMA clinical trials indicate that therapeutic effects on liver fibrosis are unclear, with potential benefits possibly involving the delay of fibrosis progression