Two molecules, GHK and securinine topped the list and were selected out of 1,309 bioactive molecules as the best agents capable to reverse expression of 54 gene sets overexpressed in malignant invasive metastatic colon cancer, which included node molecules YWHAB, MAP3K5, LMNA, APP, GNAQ, F3, NFATC2, and TGM2, involved in regulation of multiple biochemical pathways [ 27 ]
Concerns have been raised about the safety of hydroquinone in Europe, Japan, and the USA due to: Other reported cutaneous adverse effects of hydroquinone include: The safety of topical hydroquinone has not been established in pregnancy and lactation
Journal of Investigative Dermatology, 2000, 115(6): 962-968
IV therapy can support recovery and performance
purity of 98%