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The FDA's Category 2 designation means the substance may present significant safety risks when used in compounding and is prohibited in compounded medications pending further evaluation

This observation contrasts with research suggesting the combination of graded exercise therapy and cognitive behavioral therapy can alleviate fatigue, indicating ongoing debate about these therapies effectiveness [225]

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The caregiver should gently pinch the skin, insert the needle at a 90-degree angle, press the dose button, and count slowly to 6 after the dose counter reaches 0