Even though these drugs have potential mechanism to prevent or treat DPN [77,78] and very low chance to induce side effects, but large-scale randomized controlled trials to show its efficacy on DPN are scarce
332 In addition, puerarin is known to improve MAFLD by inhibiting inflammation and ferroptosis
Key hallmarks and molecular mechanisms of aging In 2023, researchers integrated and elaborated on 12 characteristics of aging, 39 including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis
Scientific reports , 6 (1), 34993
The most common side effects include: Nausea Loss of appetite Diarrhea Vomiting Dizziness Headaches Indigestion Rapid heart rate Infection Itchiness or redness at injection sites Side effects are usually mild to moderate