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Sergey Terushkin, MD, FACS, is a board-certified bariatric surgeon with 15+ years of experience, offering medical weight loss, GLP-1 therapies, and bariatric procedures at Florida Surgery And Weight Loss Center

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In initial preclinical studies, orforglipron has been shown to stimulate insulin secretion and reduce food consumption in non-human primates, and it is fully efficacious at lowering hyperglycemia in mice expressing the human GLP-1R but inactive in GLP-1R knockout animals

Gastrointestinal Distress: Nausea, vomiting, and diarrhea are common during dose escalation

While the science is still catching up, Byrne suspects that middle-aged women may be particularly vulnerable to Ozempic face because of hormonal shifts and a natural decline in collagen production during the menopause transition