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Similar content being viewed by others Introduction The World Health Organization (WHO) projected that there are approximately 46.8 million cases of Alzheimer's disease (AD) worldwide, and this number is expected to double every 20 years, with an estimated total of 131.5 million cases in 2050 [1]

Materials and methods Cell culture The human pancreatic cancer cell lines (CFPAC-1, SW1990, PANC-1, and BxPC-3) and murine pancreatic cancer cell line (Pan02) were procured from the Cell Bank of the Chinese Academy of Sciences Type Culture Collection (Shanghai, China)