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And while GLP-1 medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have taken the weight loss world by storm, here's what most most people are missing: these medications work significantly better when your hormones are also being addressed

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They demonstrated no significant elevations in IGF-1 levels and no significant changes in body composition parameters, but they did show improvements in a couple of muscle strength tests.11 Study three A separate 1997 study was more promising