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The dosage is titrated every 4 weeks

It remains unclear whether the imbalanced pharmacology or the longer half-life of tirzepatide contributes to its superior efficacy in glucose and weight reduction compared to the more balanced dual agonist, NNC0090-2746

Chronic central (intracerebroventricular) or peripheral (subcutaneous) infusion of GIP analogue in mice increased cFos neuronal activity in hypothalamic feeding center, resulting in reduced food intake and body weight

The work so far has been done in labs or with animals and is still in early stages

This delay means you feel fuller for longer after a meal, naturally reducing the desire to eat more