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Eight TSGs were downregulated upon CR ( Rnasel, Irf1, Ifi203, Sp100, Slc5a8, Apaf1, Arntl, Arhgef12 ) and nine TSGs were upregulated upon CR ( Ppara, Tgfbr2, Ndrg1, Mt2, Htatip2, Zbtb16, Glyat, Akr1b7, Fbp1 )

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