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3 Increasing GSH supply into cells to enhance protection and minimize injury has been proposed in: (1) oxidative injury to the lung from oxygen therapy, cigarette smoke, and/or atmospheric pollutants

6.4 Summary of RCTs In the RIPENACTB trial, adjunct NAC treatment with 1,200 mg twice a day in hospitalized HIV/TB patients significantly reduced circulating lipid peroxidation (malondialdehyde (MDA) levels by approximately 40%50%) and increased antioxidant defenses, including glutathione (GSH, by approximately 30%40%), compared to baseline and the standard care group

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Functions: - Antioxidant protection: neutralizes free radicals, protecting cells from oxidative stress