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Compounding pharmacies can create these medications under strict federal guidelines when the brand-name versions are in shortage, which they frequently are

Ko and D.G

doi: 10.1021/ac0007985

The issue you mention is a very real side effect - however, I address it in a completely different way by substituting the .9% Bacteriostatic Saline diluent solution with a proprietary blend of a wound wash Irrigant solution comprised of NanoMetallic Silver Oxide

Platforms that route prescriptions to a local pharmacy let you use your insurance for the medication, which can dramatically lower out-of-pocket costs for covered drugs