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All tested compounds were found to cause eryptosis by externalizing PS and activating caspase-3

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Ferroptosis in major depressive disorder Major depressive disorder (MDD), a psychiatric disorder marked by a persistent low mood and loss of interest, has become a leading cause of mental and physical disability worldwide and is widely recognized as one of the most urgent mental health issues

Most patients experienced mild to moderate illness, managed on an outpatient basis, with minimal hospitalization and no ICU admissions

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