Metal-chelating properties of curcumin confirmed protection against Amyloid- aggregation and oxidative stress suppression, most probably by inhibiting the Fenton reaction (Baum and Ng 2004)
Dig Dis Sci 60:12151222 Lee S-W, Chang C-S (2021) Impact of overlapping functional gastrointestinal disorders on the quality of life in patients with gastroesophageal reflux disease
As shown in Table 1 , inhibitors or antagonists of these targets have shown good results in animals, such as CXCR3, CXCR4, CXCL10, CXCL12, and CXCL13, especially the antibody of CXCL10 (MDX-1100) has entered clinical trials (25) ( Figure 2 )
In addition, there is an increase in lymphocyte differentiation in the direction of Th 22 and Th 17, leading to the production of Il-22 and Il-17, respectively
Yadav P, Ortega JG, Tamaki W, Chien C, Chang KC, Biswas N, et al