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A DSEA pathways analyses suggests these drugs upregulate secretion and activate pathways related to cell-cell, cell-matrix interactions, neuronal survival and differentiation suggesting possible new mechanistic targets for designing novel radioprotective drugs

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Toxicity: non-toxic at doses exceeding daily allowance by 10,000 times

can initially evade the immune system by suppressing ROS production by phagocytes, the subsequent development of inflammation in CanL is characterized by an increased influx of activated neutrophils and macrophages that generate high levels of oxidants