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Depending on who you ask you will likely get differing answers to this question

According to the governmental health agency in the United Kingdom, 181 users of Mounjaro have reported acute pancreatitis as a side effect, and 101 of those complaints were made in 2025 alone

Diagnosis is made by exclusion of alcohol abuse and other causes of liver disease (HBV-related hepatitis, HCV-related hepatitis, autoimmune liver diseases, polycystic ovary syndrome, drug-induced liver disease and congenital causes such as hereditary hemochromatosis, Wilsons disease, alpha-1 antitrypsin deficit)

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Certain people also have a hormonal imbalance that can affect their level of hunger and make it difficult to lose weight, despite healthy lifestyle practices