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The concept reframes exercise adaptation at a molecular level: part of what makes vigorous movement so beneficial may be the peptides it causes the mitochondria to secrete

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Nguyen, A

When sepsis develops, inflammatory stimuli cause the degradation of high-molecular weight HA to the low-molecular weight form, and the accumulation of this form triggers an inflammatory response with the aim of eliminating pathogens (70)

The power of fluorescence at the single molecule level was demonstrated in 2000 by Zhuang et al., who showed that fluorescence self-quenching (i.e., fluorescence quenching between identical fluorophores) is sensitive to the collapse of intrinsically disordered protein titin (Zhuang et al., 2000)