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10.1016/j.jacc.2016.02.071 58 TiniakouE.Christopher-StineL

Some patients feel an energy boost within a few days, while others with severe neurological symptoms may take several weeks of treatment before noticing improvement

But this strategy risks diluting clinical credibility

Additionally, a two-sided significance level of 20% was used for this phase 2 study (without adjustment for multiplicity), and, therefore, CI widths must be interpreted only within that context

As a result, community speculation gets cut and verified authority wins