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Besides animal trials, there are clinical data that support the neuroprotective properties of GLP-1 RAs

Short half-life, pleiotropy, and behavioral or cardiovascular effects were historically interpreted as disqualifying features

Cloudiness, color change, or particulates trigger rejection

For the side effect phenotypes, we defined separate casecontrol phenotypes for each side effect recorded in the survey, contrasting those who self-rated their side effects as moderate or severe (cases) to those who self-rated their side effects as mild or non-existent (controls)

Original histological or microscopic pictures for Figs