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FDA-approved products like Ozempic, Wegovy, Mounjaro, and Zepbound have undergone extensive premarket review

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As this oil showed anti-fatigue action toward mice received with Rotarod test and Treadmill test (16), 19 bacteria ( Enterorhabdus , Parvibacter , Akkermansia , Dubosiella , Clostridia_UCG-014 , etc.) had significant correlations with 25 changed biochemical indexes (Rotarod time, Running time, BUN, glycogen, ATP, etc.) in serum, liver, muscle, and/or colon

Heterozygous Mmut p.L690Ins/WT mice appear normal compared with wild-type ( Mmut WT/WT ) littermates, and homozygous Mmut p.L690Ins/p.L690Ins mice are characterized in detail in the Results section

Further evidence in prospective studies and randomized control trials of the safety of GLP-1 RAs during pregnancy is urgently needed before a potential recommendation can be made and its benefits can be used for future patients and mothers-to-be