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Step 3: cAMP Signaling Activation Binding to V2 receptors activates adenylyl cyclase, which increases cAMP levels

Uricase can catalyze the degradation of UA into more soluble compounds, providing fast and significant effects for gout treatment [12]

It remains to be further investigated, whether it is possible to avoid blunting of the inhibitory action by other types of inhibitors, by their combination or by combination of the diverse therapeutic modalities to efficiently limit propagation of tumor cells