Moving forward, the results of the phase 3 SURPASS clinical trial program demonstrated that tirzepatide was as effective and safe as other anti-diabetic agents, such as semaglutide and dulaglutide (SURPASS-2) (SURPASS J-mono), long-acting insulin analogs (degludec and glargine) (SURPASS-3,4), and placebo (SURPASS-1) (SURPASS-5), in managing T2DM diabetes [65,66,67,68,69]
Clment K, van den Akker E, Argente J, et al
The KRT32 protein consists of a central alpha-helical rod domain flanked by non-alpha-helical N-terminal (head) and C-terminal (tail) domains with the helical rod domain being divided into Coil 1A, 1B, and 2 subdomains by linker sequences to form the intermediate filament (IF) rod domain
High five
The prices of GLP-1 medications and similar products are raising national concerns in the U.S