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Therefore, the androgen/estrogen ratio is modified in germ cells, and if testosterone is involved in the regulation of testicular functions, estrogens are also necessary not only in the control of gonadotropins secretion but also in the modulation of the Leydig cells development and steroidogenesis, as well as in the development and/or maintenance of spermatogenesis and spermiogenesis in some mammalian species (15)

One of the things that makes Glutathione so unique is that it is one of the only antioxidants that is made in the liver

doi: 10.1038/s41593-024-01576-9

Alba et al