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Its anti-inflammatory properties may reduce the negative impact of age-related inflammation, often referred to as inflammaging. Some studies link higher spermidine intake to extended lifespan and improved mitochondrial function

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This approval is conditional, requiring confirmation from part 2 of the ESSENCE trial before full approval is considered

One study used 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) as a neuroprotectant to evaluate the neuroprotective effects of Mucuna pruriens seed extract