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In fact, it's debated in every meeting I've been to

In the SURMOUT-1 trial 2,539 patients underwent randomization to tirzepatide or placebo and were followed for 72 weeks demonstrating up to 20.9% weight reduction with maintenance dosing versus 3.1% in the placebo group for a net 17.8% weight reduction [35]

Following the instruction to rotate sites also avoids repeatedly using the same area

Protein : Adequate protein intake (0.8-1.0 g/kg body weight daily, or higher for older adults) supports both muscle and bone health during weight loss

Healthy habits, like a balanced diet and regular activity, help keep results strong