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Larger, long-term randomized controlled trials are needed to validate their efficacy, optimize dosing, and determine their role as standalone or adjunctive therapies, particularly in patients without metabolic comorbidities

Future research should prioritize high-quality trials to evaluate mitochondrial-targeted interventions, validate redox-based biomarkers, and optimize treatment protocols for improved patient outcomes

The reuse does not necessarily mean the photo is staged, but patients should know that the image is not exclusive to Willow

The method of administration depends on the condition being treated, patient preferences, and the doctors recommendation

GBCA concentration values are extrapolated from T1-weighted images and analyzed in relation to regional cerebral blood flow and vascular surface area to obtain the transfer coefficient (K trans ) of permeability per gram of brain tissue (Heye et al., 2014