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Unlike medications that mimic hormones, such as GLP-1 medications like Wegovy and Zebound, the bupropion in Wellbutrin acts directly on the brains appetite and motivation centers

[DOI] [PubMed] [Google Scholar] 10.The roles of adipokines, proinflammatory cytokines, and adipose tissue macrophages in obesity-associated insulin resistance in modest obesity and early metabolic dysfunction

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doi:10.20517/cdr.2018.08 24 Minich DM, Brown BI