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61 Arkansas enacted legislation in 2025 that mandates coverage for other treatments for severe obesity, but it specifically excludes weight-loss medications

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Thyroid cancer The prescribing information for GLP-1RA lists MTC as a contraindication, based on a preclinical rodent study demonstrating that GLP-1R activation elevates cAMP levels in rodent thyroid C-cells, stimulates calcitonin release, and promotes C-cell hyperplasia and MTC development (200)

So, if you're feeling unwell due to a deficiency, restoring B12 levels might help you feel well enough to eat normally, but it's not "making" you gain weight in an unhealthy way

The introduction of the 7.2 mg dose aims to offer a more aggressive intervention for these specific patients