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[Google Scholar] 128.Jungblut M, Aldridge D

Although glucose causes a dose-dependent inhibition of pentose phosphate pathway activity in beta cells, the major pathway for NADPH production, the cytosolic ratio of NADPH/NADP + increases during glucose-stimulated insulin release

The thermolabile T variant of the methylenetetrahydrofolate reductase ( MTHFR ) C677T polymorphism (rs1801133) is associated with a limited (oxidative) stress defense