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Pure Erythroid Leukemia Is Characterized By TP53 mutations, a Complex Karyotype with Chromosome 17 Abnormalities, and Adverse Risk Independent of Therapy Type

Comorbid Conditions : Genetic predisposition to certain health conditions like diabetes, arthritis, and thyroid disorders, which are known risk factors for CTS, can indirectly increase the risk of developing the syndrome

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4 Gut microbiota-derived metabolites and depression Bacterial compounds found in the gut can enter the bloodstream affect brain regions and can interact with nearby gut components like hormonal cells or neurons, which can subsequently send signals to the brain (161)