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NICE has not issued guidance on retatrutide, as it cannot appraise medicines that do not hold a UK marketing authorisation

They are not intended for human consumption, veterinary use, self-administration, clinical use, treatment, diagnosis, prevention, weight-loss use, medical use, wellness use or any form of personal use

Personal or family history of medullary thyroid carcinoma represents an absolute contraindication for GLP-1 related compounds including Retatrutide

Verify that any supplier provides third-party testing certificates of analysis

14 At the same time, GLP-1RAs can also inhibit glucagon secretion from pancreatic -cells