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Children with underlying medical/systemic/physical/psychological challenges, who had nonrestorable or pulpally involved teeth (either clinically or radiographically), who are Frankls definitely negative, and who refused to come for follow-up appointments were excluded

10.1016/j.tmrv.2020.12.003 Transfus

People refer to it as inflammaging for a reason, even if the term gets overused

However, methodological heterogeneity still limits inter-study comparability and hinders integrated interpretation, calling for more consistent experimental frameworks

Concurrent approach: Some add healing peptides immediately if dealing with active injuries, reasoning that healing support is needed now