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Within the past few years, several unusual syndromes believed to be associated with or part of the clinical spectrum of Hashimoto's thyroiditis have been described

otherwise, skip the missed dose and continue as scheduled

Seek urgent assessment for ulceration, signs of infection (warmth, redness, discharge), severe pain, cold or pale feet with absent pulses, or unilateral painful swelling

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For example, the landmark phase III PACIFIC trial demonstrated improved overall and progression-free survival when consolidation anti-PD-1 therapy was added to conventional chemoradiation for patients with stage III, unresectable NSCLC, leading this approach to be adopted as a standard of care for this patient population [112]