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L., Mihelc, E

We further observed that r-sFNDC5 stimulated the expression of key genes involved in fatty acid -oxidation (PPAR), mitochondrial biogenesis (PGC1), and one anti-inflammatory and insulin-sensitizing adipokine (Adipoq) (Figure 5A) and activated the ERK and AKT signaling pathways (Figure 5C)

Regensteiner JG, Golden S, Huebschmann AG et al (2015) Sex differences in the cardiovascular consequences of diabetes mellitus: a Scientific Statement From the American Heart Association