average weight loss with glp-1 Two Years After Stopping GLP-1s, Most Patients Sustain at Least Some GLP-1 vs Bariatric Surgery Study:

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The foundational mechanism papers from the Washington State University lab were retracted in April 2025 after a misconduct finding of image manipulation

Research shows they can lower systolic blood pressure by 2 to 10 mmHg on average, with tirzepatide showing the strongest effects