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In receptor-binding and cellular-signaling research, MT-2 acts as a non-selective agonist across the melanocortin receptors: MC1R (associated with melanocyte pigmentation), MC3R and MC4R (central receptors implicated in energy-homeostasis and appetite research), and MC5R

Patients had a maximum of nine cycles of mRNA-4157 (0.041 mg, administered intramuscularly) at three-week intervals

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