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doi: 10.3389/fendo.2019.00933 19 HalliwellBGutteridgeJM

It's a good idea to avoid astaxanthin if you: Are pregnant Have autoimmune problems Take immunosuppressant medication Have allergies to carotenoids Take medicines inhibiting 5-alpha-reductase Always talk to your doctor before starting the supplement

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However, folate supplementation can mask these haematological changes whilst neurological damage continues, highlighting the importance of checking B12 status before commencing folate therapy