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First, the SMIs can be easily prepared and structurally modified based on conceptually straightforward techniques

Its reliance on high fat, moderate protein, low carbohydrate intake can make it a challenge for patient adherence

The timeline will depend on safety data, final trial outcomes, and regulatory review

Ultimately, in discussions at scientific meetings on immunogenicity, scientists associated with the project attributed the systemic adverse effects to the presence of sequence impurities and, in retrospective studies, were able to link selected HLA-DR of trial participants to the unwanted immune responses

This research has made use of the NASA Exoplanet Archive, which is operated by the California Institute of Technology, under contract with NASA under the Exoplanet Exploration Program