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Clin Sci (Lond) 2017;131(1):1323

LPS activates the inflammasome complex, which cleaves IL1- into its active form [78], inhibiting downstream mechanisms necessary for GLUT4 translocation, contributing further to IR [78]

DOI: Published online: January 9, 2024 Division of Endocrinology, Department of Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands Corresponding author: Aart J

Lilly's flagship products, Mounjaro and Zepbound, alone brought in more than $36 billion in 2025, and its chief executive has estimated that 20 to 25 million patients are now taking the two companies' medicines

NCT01930188